Projects

RNDr. Narcisa Tribulová, DrSc.

International

Finished
  • Investigation of the mechanims involved in antiarrhythmic effects of melatonin
    Program: Bilateral - other
    Duration: 1. 5. 2014 – 31. 12. 2020
  • Multidisciplinary analysis of the combined effects of thyroid hormones and n-3 polyunsaturated fatty acids in rats
    Program: Inter-academic agreement
    Duration: 1. 1. 2015 – 31. 12. 2017
  • Study of cellular and molecular mechamisms involved in cardioprotective effects of red palm oil.
    Program: Bilateral - other
    Duration: 1. 1. 2010 – 31. 12. 2015
  • Investigation of the cardioprotection against injury and malignant arrhythmias induced by altered thyroid status.
    Program: Inter-governmental agreement
    Duration: 1. 1. 2014 – 31. 12. 2015
  • Investigation of the effects of omega-3 fatty acids and red palm oil in rats with altered thyroid status
    Program: Inter-academic agreement
    Duration: 1. 1. 2012 – 31. 12. 2014
  • Investigation of the cardioprotection from injury and malignant arrhythmias induced by altered thyroid statuses.
    Program: Inter-governmental agreement
    Duration: 1. 1. 2012 – 31. 12. 2013
  • Role of membranes mechanisms (omega-3 unsaturated fatty acids and connexin-43) in pathology of cardiovascular diseases
    Program: Inter-academic agreement
    Duration: 1. 1. 2008 – 31. 12. 2013
  • Chronic ischemic injury of the heart: Influence of ionizing radiation on cardiovascular system and possibilities to minimize its adverse effect
    Program: Bilateral - other
    Duration: 1. 1. 2007 – 31. 12. 2012
  • Omega-3 index and disclosure the novel mechanisms of omega-3 fatty acids actions involved in cardiac disease and arrhythmia protection.
    Program: Inter-governmental agreement
    Duration: 1. 1. 2010 – 31. 12. 2011
  • Investigation of factors determining malignant arrhythmias and their prevention by omega-3 fatty acids in cardiomyopathic rats.
    Program: Inter-academic agreement
    Duration: 1. 1. 2009 – 31. 12. 2011
  • Physiological, pharmacological, morphological and molecular studies on the role of myocardial gap junctions in initiation and termination of cardiac arrhythmias
    Program: Bilateral - other
    Duration: 1. 1. 2000 – 31. 12. 2010
  • Study of arrhythmogenic and antiarrhythmic mechanisms in the myocardium
    Program: Bilateral - other
    Duration: 1. 1. 1993 – 31. 12. 2010
  • Role of membrane mechanisms (omega-3 fatty acids and connexin-43) in pathology of cardiovascular disease
    Program: Inter-academic agreement
    Duration: 1. 1. 2008 – 31. 12. 2010

National

Current
  • Targeted suppression of pro-inflammatory and pro-fibrotic signaling pathways to prevent heart failure and occurrence of malignant arrhythmias
    Program: SRDA
    Duration: 1. 7. 2022 – 30. 6. 2026
Finished
  • The role of miRNAs in the onset and progression of cardiovascular diseases - new approach to the protection of the heart in situations of increased production of reactive oxygen species
    Program: SRDA
    Duration: 1. 7. 2020 – 30. 6. 2024
  • Are connexin channels involved in extracellular matrix remodeling of overloaded heart?
    Program: VEGA
    Duration: 1. 1. 2020 – 31. 12. 2023
  • The role of matrix metalloproteinases in pathophysiology of cardiovascular system diseases and their relation to cellular redox signaling.
    Program: SRDA
    Duration: 1. 7. 2019 – 30. 6. 2023
  • Modulation of dysregulation of extracellular matrix and intercellular communication as a heart protection from its functional failure
    Program: VEGA
    Duration: 1. 1. 2019 – 31. 12. 2022
  • Heart protection in situations of excessive formation of oxygen and nitrosyl radicals: Molecular hydrogen as a new potential therapeutic tool?
    Program: VEGA
    Duration: 1. 1. 2018 – 31. 12. 2021
  • New methods to improve diagnostics, prevention, and treatment of cardiovascular diseases with focus on oxidative stress. Protection from radiation-induced heart damage. Reperfusion injury - heart transplantation
    Program: Other projects
    Duration: 1. 12. 2018 – 31. 12. 2019
  • Investigation of regulatory mechanisms of cardiac cell-cell communication for targeted protection from heart failure.
    Program: VEGA
    Duration: 1. 1. 2016 – 31. 12. 2019
  • Study of regulation of radical and cellular signaling during hypertension and influence of novel therapies on this signaling.
    Program: SRDA
    Duration: 1. 10. 2013 – 30. 9. 2017
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    Program: VEGA
    Duration: 1. 1. 2012 – 31. 12. 2015
  • Investigation of the cardioprotection using n-3 PUFA against injury and malignant arrhythmias induced by altered thyroid status.
    Program: SRDA
    Duration: 1. 1. 2014 – 31. 12. 2015
  • Effects of melatonin, omega-3 fatty acids and aliskiren on myocardial connexin-43 and heart function in rats with CVD.
    Program: Other projects
    Duration: 12. 10. 2012 – 31. 12. 2014
  • Influence of ionizing radiation on cardiovascular system and possibilities to minimize its adverse effect
    Program: VEGA
    Duration: 1. 1. 2011 – 31. 12. 2013
  • Antiinflammatory protection of intercellular communication of cardiovascular system.
    Program: VEGA
    Duration: 1. 1. 2010 – 31. 12. 2012
  • The role of connexins in protection of the heart against letal arrhythmias and failure
    Program: VEGA
    Duration: 1. 1. 2009 – 31. 12. 2011
  • Molecular mechanisms of new drugs influencing oxidative stress - important ethiopathogenetic factor of numerous diseases
    Program: SRDA
    Duration: 1. 9. 2006 – 31. 10. 2009
  • Protection of the heart against malignant arrhythmias and heart failure.
    Program: SRDA
    Duration: 2. 5. 2006 – 30. 4. 2009
  • Molecular mechanisms of action of new drugs interfering with oxidative stress – the important factor in etiopathogenesis of numerous diseases.
    Program: SRDA
    Duration: 1. 3. 2006 – 1. 2. 2009
  • Cardiac gap junctions a potential therapeutic target
    Program: VEGA
    Duration: 1. 1. 2006 – 1. 12. 2008
  • Endothelial integrity in the injured myocardium
    Program: VEGA
    Duration: 1. 1. 2005 – 1. 12. 2007