Projects

senior scientist
D.h.c., Prof., MUDr. Ján Slezák, DrSc., FIACS

International

Finished
  • Mechanisms of radiation injury to the heart. Preventive drug treatment.
    Program: Multilateral - other
    Duration: 1. 1. 2014 – 31. 12. 2017
  • Chronic ischemic injury of the heart: Influence of ionizing radiation on cardiovascular system and possibilities to minimize its adverse effect
    Program: Bilateral - other
    Duration: 1. 1. 2007 – 31. 12. 2012

National

Current
  • Targeted suppression of pro-inflammatory and pro-fibrotic signaling pathways to prevent heart failure and occurrence of malignant arrhythmias
    Program: SRDA
    Duration: 1. 7. 2022 – 30. 6. 2026
  • New methods of treating heart failure. Prevention of oxidative stress by molecular hydrogen.
    Program: VEGA
    Duration: 1. 1. 2022 – 31. 12. 2025
  • Study of the role of innate cardioprotection in the rat myocardium evoked by non-pharmacological adaptive stimuli under normal and pathological conditions.
    Program: VEGA
    Duration: 1. 1. 2022 – 31. 12. 2025
Finished
  • The role of miRNAs in the onset and progression of cardiovascular diseases - new approach to the protection of the heart in situations of increased production of reactive oxygen species
    Program: SRDA
    Duration: 1. 7. 2020 – 30. 6. 2024
  • -
    Program: Other projects
    Duration: 1. 11. 2019 – 31. 12. 2022
  • Investigation of endotoxin effects on mechanosensoric complex in the heart of normotensive rats.
    Program: VEGA
    Duration: 1. 12. 2020 – 31. 12. 2022
  • Protection of the heart in situations of increased production of oxygen free radicals: Radiation and reperfusion injury.
    Program: SRDA
    Duration: 1. 7. 2016 – 30. 6. 2020
  • New methods to improve diagnostics, prevention, and treatment of cardiovascular diseases with focus on oxidative stress. Protection from radiation-induced heart damage. Reperfusion injury - heart transplantation
    Program: Other projects
    Duration: 1. 12. 2018 – 31. 12. 2019
  • Protection of mechanisms modulating endothelial permeability in the heart.
    Program: VEGA
    Duration: 1. 1. 2016 – 31. 12. 2019
  • Investigation of regulatory mechanisms of cardiac cell-cell communication for targeted protection from heart failure.
    Program: VEGA
    Duration: 1. 1. 2016 – 31. 12. 2019
  • -
    Program: VEGA
    Duration: 1. 1. 2015 – 31. 12. 2017
  • Yeasts in protection of endothelial intercellular connections against inflammation-induced injury.
    Program: VEGA
    Duration: 1. 1. 2013 – 31. 12. 2015
  • Proton radiation-induced cardiovascular toxicity - pathophysiology and prevention.
    Program: SRDA
    Duration: 1. 7. 2012 – 31. 12. 2015
  • The effect of the lifestyle-related risk factors on the adaptive processes in the ischemic myocardium
    Program: SRDA
    Duration: 1. 7. 2012 – 31. 12. 2015
  • Centre of excellence of SAS for research of regulatory role of nitric oxide in civilization diseases
    Program:
    Duration: 1. 8. 2011 – 30. 6. 2015
  • Influence of ionizing radiation on cardiovascular system and possibilities to minimize its adverse effect
    Program: VEGA
    Duration: 1. 1. 2011 – 31. 12. 2013
  • Antiinflammatory protection of intercellular communication of cardiovascular system.
    Program: VEGA
    Duration: 1. 1. 2010 – 31. 12. 2012
  • Protection of the heart against malignant arrhythmias and heart failure.
    Program: SRDA
    Duration: 2. 5. 2006 – 30. 4. 2009