Projects

RNDr. Barbara Szeiffová Bačová, PhD.

International

Finished
  • Investigation of the mechanims involved in antiarrhythmic effects of melatonin
    Program: Bilateral - other
    Duration: 1. 5. 2014 – 31. 12. 2020
  • Multidisciplinary analysis of the combined effects of thyroid hormones and n-3 polyunsaturated fatty acids in rats
    Program: Inter-academic agreement
    Duration: 1. 1. 2015 – 31. 12. 2017
  • Study of cellular and molecular mechamisms involved in cardioprotective effects of red palm oil.
    Program: Bilateral - other
    Duration: 1. 1. 2010 – 31. 12. 2015
  • Investigation of the cardioprotection against injury and malignant arrhythmias induced by altered thyroid status.
    Program: Inter-governmental agreement
    Duration: 1. 1. 2014 – 31. 12. 2015
  • Investigation of the effects of omega-3 fatty acids and red palm oil in rats with altered thyroid status
    Program: Inter-academic agreement
    Duration: 1. 1. 2012 – 31. 12. 2014
  • Omega-3 index and disclosure the novel mechanisms of omega-3 fatty acids actions involved in cardiac disease and arrhythmia protection.
    Program: Inter-governmental agreement
    Duration: 1. 1. 2010 – 31. 12. 2011
  • Role of membrane mechanisms (omega-3 fatty acids and connexin-43) in pathology of cardiovascular disease
    Program: Inter-academic agreement
    Duration: 1. 1. 2008 – 31. 12. 2010

National

Current
  • Targeted suppression of pro-inflammatory and pro-fibrotic signalling pathways to prevent life-threatening heart failure and malignant arrhythmias
    Program: VEGA
    Duration: 1. 1. 2023 – 31. 12. 2026
  • Targeted suppression of pro-inflammatory and pro-fibrotic signaling pathways to prevent heart failure and occurrence of malignant arrhythmias
    Program: SRDA
    Duration: 1. 7. 2022 – 30. 6. 2026
  • New aspects of cardioprotection by natural antioxidants: role of ageing and lifestyle-related comorbidities
    Program: SRDA
    Duration: 1. 7. 2022 – 30. 6. 2026
Finished
  • The role of miRNAs in the onset and progression of cardiovascular diseases - new approach to the protection of the heart in situations of increased production of reactive oxygen species
    Program: SRDA
    Duration: 1. 7. 2020 – 30. 6. 2024
  • Are connexin channels involved in extracellular matrix remodeling of overloaded heart?
    Program: VEGA
    Duration: 1. 1. 2020 – 31. 12. 2023
  • Modulation of dysregulation of extracellular matrix and intercellular communication as a heart protection from its functional failure
    Program: VEGA
    Duration: 1. 1. 2019 – 31. 12. 2022
  • New methods to improve diagnostics, prevention, and treatment of cardiovascular diseases with focus on oxidative stress. Protection from radiation-induced heart damage. Reperfusion injury - heart transplantation
    Program: Other projects
    Duration: 1. 12. 2018 – 31. 12. 2019
  • Investigation of regulatory mechanisms of cardiac cell-cell communication for targeted protection from heart failure.
    Program: VEGA
    Duration: 1. 1. 2016 – 31. 12. 2019
  • Protection of the heart from maladaptive extracellular matrix remodeling and searching the mechanisms of its regression.
    Program: VEGA
    Duration: 1. 1. 2015 – 31. 12. 2018
  • Matrix-metalloproteinases, microRNAs and deformability of erythrocytes as a novel diagnostic and predictive biomarkers of heart failure
    Program: VEGA
    Duration: 1. 1. 2014 – 31. 12. 2017
  • Study of regulation of radical and cellular signaling during hypertension and influence of novel therapies on this signaling.
    Program: SRDA
    Duration: 1. 10. 2013 – 30. 9. 2017
  • -
    Program: VEGA
    Duration: 1. 1. 2012 – 31. 12. 2015
  • Investigation of the cardioprotection using n-3 PUFA against injury and malignant arrhythmias induced by altered thyroid status.
    Program: SRDA
    Duration: 1. 1. 2014 – 31. 12. 2015